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Ginkgolide A
CAS No. 15291-75-5
Ginkgolide A( Ginkgolide A | BN 52020 | BN 52020 )
Catalog No. M18065 CAS No. 15291-75-5
Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 30 | In Stock |
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| 25MG | 56 | In Stock |
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| 50MG | 88 | In Stock |
|
| 100MG | 143 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameGinkgolide A
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NoteResearch use only, not for human use.
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Brief DescriptionGinkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.
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DescriptionGinkgolide A is GSK-3β inhibitor and potential PXR agonist found in Ginkgo. It decreases phosphorylation of Tau protein, prevents neointimal hyperplasia and decreases anxiety.
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In Vitro——
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In Vivo——
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SynonymsGinkgolide A | BN 52020 | BN 52020
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PathwayMAPK/ERK Signaling
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Targetp38 MAPK
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RecptorGABAR
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number15291-75-5
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Formula Weight408.4
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Molecular FormulaC20H24O9
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Purity>98% (HPLC)
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SolubilityDMSO : 100 mg/mL 244.86 mM
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SMILESO1[C@H]2C[C@]34[C@@H]5OC(=O)[C@]3(O[C@@H]3OC(=O)[C@H](O)[C@]43[C@H](C(C)(C)C)C5)[C@@]2(O)[C@H](C)C1=O
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Chemical Name9H-1,7a-(Epoxymethano)-1H,6aH-cyclopenta(c)furo(2,3-b)furo(3',2':3,4)cyclopenta(1,2-d)furan-5,9,12(4H)-trione, 3-(1,1-dimethylethyl)hexahydro-4,7b-dihydroxy-8-methyl-, (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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PAF (C16)
PAF (C16) is a potent MAPK and MEK/ERK activator that induces increased vascular permeability. PAF (C16) (PAF (C16)) is a platelet-activating factor, a phospholipid-derived mediator and a ligand for PAF G protein-coupled receptor (PAFR). PAF (C16) has shown anti-apoptotic and anti-inflammatory activity in vitro, inhibiting Caspase-dependent apoptosis by interacting with its receptor (PAF-R) to perform cell signaling.
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SB 203580
A specific p38 MAPK inhibitor with IC50 of 0.6 uM; shows selectivity over JNK, p42 MAPK, p90 S6K, p70 S6K, PKA, etc.
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Darizmetinib
Darizmetinib (HRX215, HRX-0215) is an MKK4 inhibitor. Inhibition of MKK4 leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and liver regeneration.
